Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas

Résumé

To identify novel epigenetic signatures that could provide predictive information that is complementary to promoter methylation status of the O-6-methylguanine-DNA methyltransferase (MGMT) gene for predicting temozolomide (TMZ) response, among glioblastomas (GBMs) without glioma-CpGs island methylator phenotype (G-CIMP)


Auteurs, date et publication :

Auteurs An-An Yin , Ya-Long He , Amandine Etcheverry , Yu-He Liu , Marc Aubry , Jill Barnholtz-Sloan , Bo-Lin Liu , Jean Mosser , Zi-Fan Lu , Xiang Zhang

Publication : Clinical Epigenetics

Date : 2019

Volume : 11

Issue : 1

Pages : 76


Catégorie(s)

#CNRS #EcoGenO #Université de Rennes