Résumé
Finding more sustainable ways to produce food is a major challenge for humanity in the face of biodiversity extinction and climate change. Consequently, research on the ability of agroecosystems to provide multiple functions is growing. In this regard, the relative importance of organic farming and landscape-scale measures for improving multifunctionality has recently been debated. We investigated the effects of farming system (conventional vs. organic) at field scale, total length of hedgerows in the landscape and their interaction on the multifunctionality of 40 winter cereal fields in Brittany (France). Our multifunctionality assessment integrated 21 indicators of five agroecosystem goods: biodiversity conservation, nutrient cycling and soil structure, pest and disease regulation, food production and socio-economic performance. Many indicators of biodiversity conservation, pest and disease regulation, and socio-economic performance were higher in organic than in conventional systems. However, indicators of nutrient cycling and soil structure did not improve and food production was much lower in organic systems. Total hedgerow length in the landscape had less influence than organic farming on indicators, although we observed positive interactions. Granivorous carabid abundance and semi-net margin were highest in organic fields located in well-preserved hedgerow landscapes. Synthesis and applications. Our study suggests that field-scale organic farming is necessary to promote biodiversity conservation and associated ecological functioning in crop fields, whereas landscape-scale preservation of semi-natural habitats alone is likely insufficient. Preservation of hedgerows in the landscape brings additional ecological and socio-economic benefits for organic systems without compromising agricultural production. More broadly, our results call for more ambitious research into the myriad possible combinations of farming practices and agri-environmental measures at both field and landscape scales, to improve both below-ground and above-ground functioning.
Auteurs, date et publication :
Auteurs Sébastien Boinot , Audrey Alignier , Stéphanie Aviron , Colette Bertrand , Nathalie Cheviron , Gwendoline Comment , Emma Jeavons , Cécile Le Lann , Samuel Mondy , Christian Mougin , Pierre-Antoine Précigout , Claire Ricono , Corinne Robert , Grégoire Saias , Philippe Vandenkoornhuyse , Cendrine Mony
Publication : Journal of Applied Ecology
Date : 2026
Volume : 62
Issue : 1
Pages : 53-63
Catégorie(s)
#BiochemEnv #CNRS #EcoGenO #GenosolRésumé
Agricultural intensification has been demonstrated to induce a loss of biodiversity. Despite the key role of symbiotic microorganisms in plant nutrition and protection, the impact of agricultural intensification on these microorganisms is not fully understood. Organic farming and field edges (as semi-natural elements) may promote a higher microbial diversity thanks to lower anthropic disturbance and higher plant diversity. We sampled wheat individuals in pairs of wheat fields (one organic and one conventional) along a distance gradient to the edges (hedgerow vs. grassy), in 20 landscape windows selected along an uncorrelated gradient of organic farming and hedgerow density. We demonstrated that organic farming shaped microbial composition and increased fungal and bacterial richness, while hedgerows had a neutral or negative effect on richness depending on the microbial phyla considered. In contrast to bacteria, fungal communities were heterogeneously distributed within fields, having a higher diversity for some phyla close to field edges. Overall we highlighted that fungi responded more to the field scale while bacteria were more affected by landscape scale. The effect of agricultural intensification on plant microbiota and therefore on the functions provided by microorganisms to the plants has to be considered at a multiple spatial scale—from field to landscape.
Auteurs, date et publication :
Auteurs Claire Ricono , Philippe Vandenkoornhuyse , Stéphanie Aviron , Olivier Jambon , Sophie Michon-Coudouel , Romain Causse-Vedrines , Solène Mauger , Cendrine Mony
Publication : FEMS Microbiology Ecology
Date : 2022
Volume : 98
Issue : 3
Pages : fiac027
Catégorie(s)
#CNRS #EcoGenO #Université de RennesRésumé
Due to the importance of arbuscular mycorrhizal fungi (AMF) in ecosystem productivity, a key ecological question is how do their communities assemble? As plant spatial patterns constitute a mosaic of AM fungi habitats, we hypothesized that AM fungal community assembly is determined by plant community structure, both in space and time. We tested our hypothesis by sampling individuals of two host-plant species, Brachypodium pinnatum and Elytrigia repens, from experimental communities cultivated in mesocosms, and assessed their AM fungal root colonizers by mass sequencing. We related AM fungal community structure to the distribution of neighbouring plant species at different spatio-temporal scales. We demonstrated that AM fungal community assembly depends mostly on past plant spatial patterns at a small spatial scale (5 cm), indicating that plants growing at given locations leave a footprint on the AM fungi community. This spatial scale of response was also influenced by the host-plant species, probably by its clonal propagation. Synthesis. Overall, we highlighted that processes involved in Arbuscular mycorrhizal (AM) fungal community assembly do not operate at the rough scale of the overall plant community mosaic but are instead locally determined, delineating the AM fungal ‘eye-view’ of the host-plant community.
Auteurs, date et publication :
Auteurs Anne-Kristel Bittebiere , Philippe Vandenkoornhuyse , Elodie Maluenda , Agnès Gareil , Alexandra Dheilly , Sophie Coudouel , Mathieu Bahin , Cendrine Mony
Publication : Journal of Ecology
Date : 2025
Volume : 108
Issue : 2
Pages : 546-560
Catégorie(s)
#CNRS #EcoGenO #Université de RennesRésumé
The Publisher regrets that this article is an accidental duplication of an article that has already been published, https://doi.org/10.1016/S0007-4551(18)30393-X. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal.
Auteurs, date et publication :
Auteurs Alexandra Frelau , Marc Pracht , Samuel Le Sourd , Alexandra Lespagnol , Romain Corre , Cédric Ménard , Karin Tarte , Jean Mosser , Julien Edeline
Publication : Bulletin du Cancer
Date : 2018
Catégorie(s)
#CNRS #EcoGenO #Université de RennesAuteurs, date et publication :
Auteurs Anne-Laure Besnard , Daniel J. Park , Bernard J. Pope , Fleur Hammet , Sophie Michon-Coudouel , Marine Biget , Stacy A. Krueger-Hadfield , Stéphane Mauger , Eric J. Petit
Date : 2023
Catégorie(s)
#CNRS #EcoGenO #Université de RennesAuteurs, date et publication :
Auteurs Olivier Bochet , Lorine Bethencourt , Alexis Dufresne , Julien Farasin , Mathieu Pédrot , Thierry Labasque , Eliot Chatton , Nicolas Lavenant , Christophe Petton , Benjamin W. Abbott , Luc Aquilina , Tanguy Le Borgne
Publication : Nature Geoscience
Date : 2025
Volume : 13
Issue : 2
Pages : 149-155
Catégorie(s)
#CNRS #EcoGenO #Université de RennesRésumé
Improving feed efficiency (FE) is a major challenge in pig production. This complex trait is characterized by a high variability. Therefore, the identification of predictors of FE may be a relevant strategy to reduce phenotyping efforts in breeding and selection programs. The aim of this study was to investigate the suitability of expressed muscle genes in prediction of FE traits in growing pigs. The approach considered different transcriptomics experiments to cover a large range of FE values and identify reliable predictors.
Auteurs, date et publication :
Auteurs Farouk Messad , Isabelle Louveau , Basile Koffi , Hélène Gilbert , Florence Gondret
Publication : BMC Genomics
Date : 2019
Volume : 20
Issue : 1
Pages : 659
Catégorie(s)
#CNRS #EcoGenO #Université de RennesRésumé
Considering the plant microbiota, temporal changes are expected depending on plant development stages and environmental pressures because of modifications in plant requirements and available soil microbial reservoir.
Auteurs, date et publication :
Auteurs Marine Biget , Cendrine Mony , Tingting Wang , Ning Ling , Adèle Miteul , Olivier Jambon , Romain Causse-Védrines , Sophie Michon-Coudouel , Maxime Hervé , Véronique Chable , Sabrina Pernet , Philippe Vandenkoornhuyse
Publication : Plant and Soil
Date : 2024
Volume : 494
Issue : 1
Pages : 217-233
Catégorie(s)
#CNRS #EcoGenO #Université de RennesRésumé
Runt-related transcription factor 1 (RUNX1) is a well-known master regulator of hematopoietic lineages but its mechanisms of action are still not fully understood. Here, we found that RUNX1 localizes on active chromatin together with Far Upstream Binding Protein 1 (FUBP1) in human B-cell precursor lymphoblasts, and that both factors interact in the same transcriptional regulatory complex. RUNX1 and FUBP1 chromatin localization identified c-KIT as a common target gene. We characterized two regulatory regions, at +700 bp and +30 kb within the first intron of c-KIT, bound by both RUNX1 and FUBP1, and that present active histone marks. Based on these regions, we proposed a novel FUBP1 FUSE-like DNA-binding sequence on the +30 kb enhancer. We demonstrated that FUBP1 and RUNX1 cooperate for the regulation of the expression of the oncogene c-KIT. Notably, upregulation of c-KIT expression by FUBP1 and RUNX1 promotes cell proliferation and renders cells more resistant to the c-KIT inhibitor imatinib mesylate, a common therapeutic drug. These results reveal a new mechanism of action of RUNX1 that implicates FUBP1, as a facilitator, to trigger transcriptional regulation of c-KIT and to regulate cell proliferation. Deregulation of this regulatory mechanism may explain some oncogenic function of RUNX1 and FUBP1.
Auteurs, date et publication :
Auteurs Lydie Debaize , Hélène Jakobczyk , Stéphane Avner , Jérémie Gaudichon , Anne-Gaëlle Rio , Aurélien A Sérandour , Lena Dorsheimer , Frédéric Chalmel , Jason S Carroll , Martin Zörnig , Michael A Rieger , Olivier Delalande , Gilles Salbert , Marie-Dominique Galibert , Virginie Gandemer , Marie-Bérengère Troadec
Publication : Nucleic Acids Research
Date : 2018
Volume : 46
Issue : 21
Pages : 11214-11228
Catégorie(s)
#CNRS #EcoGenO #Université de RennesRésumé
Glioblastoma (GB) is the most common and aggressive tumor of the brain. Genotype-based approaches and independent analyses of the transcriptome or the proteome have led to progress in understanding the underlying biology of GB. Joint transcriptome and proteome profiling may reveal new biological insights, and identify pathogenic mechanisms or therapeutic targets for GB therapy. We present a comparison of transcriptome and proteome data from five GB biopsies (TZ) vs their corresponding peritumoral brain zone (PBZ). Omic analyses were performed using RNA microarray chips and the isotope-coded protein label method (ICPL).
Auteurs, date et publication :
Auteurs Jean-Michel Lemée , Anne Clavreul , Marc Aubry , Emmanuelle Com , Marie de Tayrac , Jean Mosser , Philippe Menei
Publication : BMC Molecular Biology
Date : 2018
Volume : 19
Issue : 1
Pages : 13