Auteurs, date et publication :
Auteurs Thierry Burgeot
Date : 2025
Catégorie(s)
#INRAE #PEARLRésumé
The antibodies of jawless vertebrates consist of leucine-rich repeat arrays encoded by somatically assembled VLRB genes. It is unknown how the incomplete germline VLRB loci are converted into functional antibody genes during B lymphocyte development in lampreys. In Lampetra planeri larvae lacking the cytidine deaminase CDA2 gene, VLRB assembly fails, whereas the T lineage-associated VLRA and VLRC antigen receptor gene assemblies occur normally. Thus, CDA2 acts in a B cell lineage-specific fashion to support the somatic diversification of VLRB antibody genes. CDA2 is closely related to activation-induced cytidine deaminase (AID), which is essential for the elaboration of immunoglobulin gene repertoires in jawed vertebrates. Our results thus identify a convergent mechanism of antigen receptor gene assembly and diversification that independently evolved in the two sister branches of vertebrates.
Auteurs, date et publication :
Auteurs Ryo Morimoto , Connor O’meara , Stephen Holland , Inês Trancoso , Ahmed Souissi , Michael Schorpp , Danièle Vassaux , Norimasa Iwanami , Orlando Giorgetti , Guillaume Evanno , Thomas Boehm
Publication : Science Immunology
Date : 2020
Volume : 5
Issue : 45
Pages : eaba0925
Catégorie(s)
#INRAE #PEARLAuteurs, date et publication :
Auteurs Joël Aubin
Date : 2025
Catégorie(s)
#INRAE #PEARLAuteurs, date et publication :
Auteurs Alpar Barsi , Tjalling Jager , Marc Collinet , Laurent Lagadic , Virginie Ducrot
Publication : Environmental Toxicology and Chemistry
Date : 2014
Pages : n/a-n/a
Catégorie(s)
#INRAE #PEARLAuteurs, date et publication :
Auteurs Yannick Bayona , Marc Roucaute , Caroline Gorzerino , Ana Roucaute , Kevin Cailleaud , Anne Bassères , Laurent Lagadic , Thierry Caquet
Date : 2012
Catégorie(s)
#INRAE #PEARLAuteurs, date et publication :
Auteurs Gaétan Pottier
Date : 2025
Catégorie(s)
#INRAE #PEARLAuteurs, date et publication :
Auteurs Claire Duchet , Marília Mitie Inafuku , Thierry Caquet , Michel Larroque , Evelyne Franquet , Christophe Lagneau , Laurent Lagadic
Publication : Ecotoxicology and Environmental Safety
Date : 2011
Volume : 74
Issue : 4
Pages : 800-810
Catégorie(s)
#INRAE #PEARLRésumé
In temperate fish polyculture, common carp (Cyprinus carpio) and roach (Rutilus rutilus) are two fish species commonly reared in the same ponds. In the natural environment, these two species are considered omnivorous and may compete for food sources. However, few is known about their trophic behavior in polyculture ponds. The aim of our study was to use carbon and nitrogen stable isotope analysis to characterize trophic niche partitioning between both fish species reared in semi-intensive (fed) and extensive (non-fed) ponds. Fish growth performance was higher in semi-intensive than in extensive ponds. In semi-intensive ponds, δ13C and δ15N values of fish indicated that carp consumed mainly formulated feed, whereas roach also consumed natural food sources. In extensive ponds, δ13C and δ15N values of carp and roach indicated that both fish species did not use the same food sources. Regardless of the type of pond, standard ellipse areas, proxies of the estimated trophic niche size, were significantly smaller for carp than for roach and did not overlap, confirming that roach had more trophic plasticity than carp. Results of this study confirmed that carp and roach are good candidates to be rear in the same pond because they are able to adapt their trophic behavior to reduce trophic competition.
Auteurs, date et publication :
Auteurs Sarah Nahon , Jean-Marc Roussel , Christophe Jaeger , Christophe Menniti , Philippe Kerhervé , Jean-Michel Mortillaro , Joël Aubin
Publication : Aquaculture
Date : 2020
Volume : 522
Pages : 735162
Catégorie(s)
#INRAE #PEARLAuteurs, date et publication :
Auteurs Arnaud Gaigher , Sophie Launey , Emilien Lasne , Anne-Laure Besnard , Guillaume Evanno
Publication : Conservation Genetics Resources
Date : 2012
Catégorie(s)
#INRAE #PEARLRésumé
In the last 10 years, many atypical novel members of Brucella species have been reported, including several Brucella inopinata-like strains in wild-caught and “exotic” amphibians from various continents. In 2017, a strain of Brucella was isolated for the first time in animals from a French farm producing frogs—Pelophylax ridibundus—for human consumption and identified as B. microti-like. Following this first isolation, investigations were performed in this farm as well as in the farm of the research unit that provided the domestic frog strain to estimate the prevalence of B. microti-like infection and its presence in the surrounding environment. Farming practices were investigated and samples including frogs at different development stages, surface tank swabs, water, feed and soil were analysed by real-time PCR and bacteriological methods. High B. microti-like prevalence values (higher than 90%) were obtained in frog samples in the commercial farm, and its presence was highlighted in the environmental samples except feed. In the research unit farm, B. microti-like species was also isolated and detected in frog and environmental samples. These results show that B. microti-like organisms are able to colonize amphibians and persist in their environment. Its presence could constitute a possible risk for consumers and workers proving the importance of assessing the zoonotic and pathogenic potentials of these new and atypical Brucella species.
Auteurs, date et publication :
Auteurs Maryne Jaÿ , Luca Freddi , Virginie Mick , Benoit Durand , Guillaume Girault , Ludivine Perrot , Benoit Taunay , Thomas Vuilmet , Didier Azam , Claire Ponsart , Gina Zanella
Publication : Transboundary and Emerging Diseases
Date : 2025
Volume : 67
Issue : 2
Pages : 617-625